SPRED2

sprouty related EVH1 domain containing 2
OMIM: 609292, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Green SPRED2 in Familial non syndromic congenital heart disease Level 3: Congenital heart disease Level 2: Cardiovascular disorders Version 1.80	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes developmental delay intellectual disability cardiac defects short stature skeletal anomalies a typical facial gestalt
Green SPRED2 in DDG2P Version 3.87 Latest signed off version: v3.1 (22 Mar 2023) Component of the following Super Panels: Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources DD-Gene2Phenotype Expert Review Green Phenotypes SPRED2-related Noonan syndrome
Green SPRED2 in Growth failure in early childhood Version 3.88 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Literature Phenotypes Noonan syndrome 14, OMIM:619745
Green SPRED2 in Intellectual disability - microarray and sequencing Level 3: Neurodevelopmental disorders Level 2: Neurology and neurodevelopmental disorders Version 5.532 Latest signed off version: v5.0 (22 Mar 2023) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Literature Phenotypes developmental delay intellectual disability cardiac defects short stature skeletal anomalies a typical facial gestalt
Green SPRED2 in RASopathies Level 3: RASopathies Level 2: Dysmorphic and congenital abnormality syndromes Version 1.81	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes developmental delay intellectual disability cardiac defects short stature skeletal anomalies a typical facial gestalt
Green SPRED2 in Paediatric or syndromic cardiomyopathy Version 3.46 Latest signed off version: v3.0 (22 Mar 2023) Component of the following Super Panels: Unexplained death in infancy and sudden unexplained death in childhood	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Literature Phenotypes developmental delay intellectual disability cardiac defects short stature skeletal anomalies a typical facial gestalt