SRC

SRC proto-oncogene, non-receptor tyrosine kinase
OMIM: 190090, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Red SRC in GI tract tumours

Level 3: GI tract
Level 2: Tumour syndromes
Version 1.22

review Not set
Sources
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • ?Colon cancer, advanced
Green SRC in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.175

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Other
Phenotypes
  • Thrombocytopenia, Bleeding and myelofibrosis
  • ?Thrombocytopenia 6,616937
  • Platelet disorder
Green SRC in Bleeding and platelet disorders


Version 3.7
Latest signed off version: v3.0 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Wessex and West Midlands GLH
Phenotypes
  • 616937 ?Thrombocytopenia 6
Green SRC in Cytopenia - NOT Fanconi anaemia


Version 3.21
Latest signed off version: v3.0 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Expert review Green
  • NHS GMS
  • North West GLH
  • London South GLH
  • Yorkshire and North East GLH
  • Wessex and West Midlands GLH
Phenotypes
  • ?Thrombocytopenia 6, 616937
Green SRC in Severe Paediatric Disorders


Version 1.182

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Colon cancer, advanced, somatic, 114500
  • ?Thrombocytopenia 6, 616937