Cytopenia - NOT Fanconi anaemia
Gene: SRC
Gene reviewed due to Haematology Specialist Test Group considering the inclusion of relevant neutropenia thrombocytopenia genes. The Specialist Test Group 21st October 2019 (consisting of 4 centres: WWMGLH, NWGLH, YNEGLH, LSGLH) all agreed that there is enough evidence to rate this gene Green. Additional comments from Haematology Specialist Test Group (Copy of Extra genes R91_consensus_v2.xlsx) 21st October 2019. Wessex and West Midlands GLH: Thrombocytopenia 6; limited evidence but green on R90 so also green for R91; North West GLH:Thrombocytopenia 6; Yorkshire and North East GLH: no comment submitted; London South GLH: no comment submittedCreated: 4 Nov 2019, 7:30 p.m. | Last Modified: 4 Nov 2019, 7:30 p.m.
Panel Version: 0.135
Source Expert Review Green was added to SRC. Rating Changed from Red List (low evidence) to Green List (high evidence)
Source Expert review Green was added to SRC.
Mode of inheritance for gene SRC was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes ?Thrombocytopenia 6, 616937 for gene: SRC
gene: SRC was added gene: SRC was added to Cytopenia - NOT Fanconi anaemia. Sources: Wessex and West Midlands GLH,Yorkshire and North East GLH,London South GLH,North West GLH,NHS GMS Mode of inheritance for gene: SRC was set to