TMC8

transmembrane channel like 8
OMIM: 605829, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels

Green TMC8 in COVID-19 research


Level 2: Viral research
Version 1.60

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • Melbourne Genomics Health Alliance Immunology Flagship
  • NHS GMS
  • North West GLH
  • London North GLH
  • Expert Review Green
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
  • Literature
Phenotypes
  • HPV (group B1) infections and cancer of the skin (typical EV)
  • Epidermodysplasia verruciformis, 226400
  • Defects in Intrinsic and Innate Immunity
  • Epidermodysplasia Verruciformis

Green TMC8 in Pigmentary skin disorders


Version 1.3
Signed off v.1.2 on 19 Feb 2020

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Green
Phenotypes
  • EPIDERMODYSPLASIA VERRUCIFORMIS, SUSCEPTIBILITY TO, 2
  • Epidermodysplasia verruciformis 2, 618231
  • EV2

Green TMC8 in Epidermodysplasia verruciformis


Version 1.3
Signed off v.1.2 on 19 Feb 2020

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Green
Phenotypes
  • Epidermodysplasia verruciformis 2, 618231

Green TMC8 in Primary immunodeficiency


Version 2.175
Signed off v.2.1 on 24 Feb 2020

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • Expert Review Green
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Epidermodysplasia verruciformis, 226400
  • HPV (group B1) infections and cancer of the skin (typical EV)
  • Defects in Intrinsic and Innate Immunity

No list TMC8 in Multiple monogenic benign skin tumours


Version 1.3
Signed off v.1.2 on 19 Feb 2020

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Removed
  • London North GLH
  • NHS GMS
Phenotypes
  • Epidermodysplasia verruciformis 2, 618231
  • Epidermodysplasia verruciformis

Green TMC8 in Severe Paediatric Disorders


Version 1.10

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Epidermodysplasia verruciformis 2, 618231