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Monogenic viral susceptibility

Gene: TMC8

Red List (low evidence)

TMC8 (transmembrane channel like 8)
EnsemblGeneIds (GRCh38): ENSG00000167895
EnsemblGeneIds (GRCh37): ENSG00000167895
OMIM: 605829, Gene2Phenotype
TMC8 is in 4 panels

1 review

Ellen McDonagh (Genomics England Curator)

In these patients, lesions degenerate into nonmelanoma skin cancers caused by a specific group of human papillomaviruses (HPV), the Epidermodysplasia Verruciformis-associated oncogenic beta-HPV (EV-HPV) (PMID:26621750).
Created: 14 Mar 2017, 2:35 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Epidermodysplasia Verruciformis

Publications

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Literature
Phenotypes
  • Epidermodysplasia Verruciformis
OMIM
605829
Clinvar variants
Variants in TMC8
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

14 Mar 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

TMC8 was added to Monogenic viral susceptibilitypanel. Sources: Literature

14 Mar 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

TMC8 was created by ellenmcdonagh