Genes in panel
STRs in panel
Prev Next

COVID-19 research

Gene: FCGR1A

Red List (low evidence)

FCGR1A (Fc fragment of IgG receptor Ia)
EnsemblGeneIds (GRCh38): ENSG00000150337
EnsemblGeneIds (GRCh37): ENSG00000150337
OMIM: 146760, Gene2Phenotype
FCGR1A is in 2 panels

3 reviews

Catherine Snow (Genomics England)

Comment on list classification: FCGR1 is on the Immunoplex Panel offered by the University of Washington Department of Laboratory Medicine however there is currently no link to alleles and disease (PMID: 31057544)
Created: 8 Apr 2020, 6:30 a.m. | Last Modified: 8 Apr 2020, 6:30 a.m.
Panel Version: 0.62

Sophie Hambleton (Newcastle University)

Red List (low evidence)

Not linked to Mendelian immune disorder
Created: 11 Jun 2018, 2:29 p.m.

Louise Daugherty (Genomics England Curator)

I don't know

External expert review notes Red status due to no evident link to mendelian immunodeficiency, so I have kept this gene Red on this panel
Created: 12 Jun 2018, 12:47 p.m.
Original metadata downloaded from ESID Registry. ESID_Gene_original: FCGR1A, PanelApp HGNC gene symbol check: FCGR1A, ESID classification: Main_category/ Sub_category/ PID_Diagnosis Other well defined PIDs / Fc receptor deficiencies / Fc receptor deficiencies
Created: 17 Apr 2018, 12:29 p.m.

Details

Mode of Inheritance
Unknown
Sources
  • Expert Review Red
Phenotypes
  • Fc receptor deficiencies
OMIM
146760
Clinvar variants
Variants in FCGR1A
Penetrance
None
Panels with this gene

History Filter Activity

8 Apr 2020, Gel status: 1

Entity classified by Genomics England curator

Catherine Snow (Genomics England)

Gene: fcgr1a has been classified as Red List (Low Evidence).

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: FCGR1A was added gene: FCGR1A was added to Viral susceptibility. Sources: Expert Review Red,ESID Registry 20171117 Mode of inheritance for gene: FCGR1A was set to Unknown Phenotypes for gene: FCGR1A were set to Fc receptor deficiencies