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STRs in panel
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COVID-19 research

Gene: ITGAL

Red List (low evidence)

ITGAL (integrin subunit alpha L)
EnsemblGeneIds (GRCh38): ENSG00000005844
EnsemblGeneIds (GRCh37): ENSG00000005844
OMIM: 153370, Gene2Phenotype
ITGAL is in 1 panel

1 review

Rebecca Foulger (Genomics England curator)

Added to panel based on presence in the UniProt COVID portal:
https://covid-19.uniprot.org/uniprotkb/P20701. Data in PMID:18020948 suggests ITGAL (LFA-1) to be an attachment factor or the receptor for SARS-CoV on human leukocytes. Kept rating as Red awaiting Expert Review.
Sources: Literature, Other
Created: 23 Apr 2020, 4:37 p.m.

Mode of inheritance
Unknown

Publications

Details

Mode of Inheritance
Unknown
Sources
OMIM
153370
Clinvar variants
Variants in ITGAL
Penetrance
None
Publications
Panels with this gene

History Filter Activity

23 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications

Rebecca Foulger (Genomics England curator)

gene: ITGAL was added gene: ITGAL was added to Viral susceptibility. Sources: Literature,Other Mode of inheritance for gene: ITGAL was set to Unknown Publications for gene: ITGAL were set to 18020948