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STRs in panel
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COVID-19 research

Gene: LYZ

Red List (low evidence)

LYZ (lysozyme)
EnsemblGeneIds (GRCh38): ENSG00000090382
EnsemblGeneIds (GRCh37): ENSG00000090382
OMIM: 153450, Gene2Phenotype
LYZ is in 4 panels

2 reviews

Sophie Hambleton (Newcastle University)

Red List (low evidence)

Agree red rating
Created: 23 Oct 2019, 7:08 a.m. | Last Modified: 23 Oct 2019, 7:08 a.m.
Panel Version: 1.132

Louise Daugherty (Genomics England Curator)

Red List (low evidence)

More relevant to Amyloidosis panel: already green there (https://panelapp.genomicsengland.co.uk/panels/502/). New gene added after review of potential new genes for PID by the Immunology Test Group. This gene was noted as being only theoretical for PID so was rated as Red by the group.
Created: 27 Sep 2019, 2:46 p.m. | Last Modified: 27 Sep 2019, 2:46 p.m.
Panel Version: 1.132

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
Phenotypes
  • Amyloidosis, renal, 105200
OMIM
153450
Clinvar variants
Variants in LYZ
Penetrance
None
Panels with this gene

History Filter Activity

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: LYZ was added gene: LYZ was added to Viral susceptibility. Sources: Expert Review Red,NHS GMS,London North GLH Mode of inheritance for gene: LYZ was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: LYZ were set to Amyloidosis, renal, 105200