LYZ

lysozyme
OMIM: 153450, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green LYZ in Periodic fever syndromes

Level 3: Multi-system inflammatory/autoimmune disorders
Level 2: Rheumatological disorders
Version 1.34

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Eligibility statement prior genetic testing
  • Illumina TruGenome Clinical Sequencing Services
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Amyloidosis, renal, 105200
  • Familial Visceral Amyloidosis
Red LYZ in COVID-19 research


Level 2: Viral research
Version 1.146

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Red
  • NHS GMS
  • Expert Review Red
  • London North GLH
Phenotypes
  • Amyloidosis, renal, 105200
Green LYZ in Hereditary systemic amyloidosis


Level 2: Renal
Version 1.28
Latest signed off version: v1.24 (30 Apr 2025)

Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease
  • review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • NHS GMS
    • Expert Review Green
    Phenotypes
    • Amyloidosis, renal 105200
    Red LYZ in Primary immunodeficiency or monogenic inflammatory bowel disease


    Level 2: Immunology
    Version 8.78
    Latest signed off version: v8.0 (30 Apr 2025)

    review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • NHS GMS
    • Expert Review Red
    • London North GLH
    Phenotypes
    • Amyloidosis, renal, 105200