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COVID-19 research

Gene: SLC2A1

Amber List (moderate evidence)

SLC2A1 (solute carrier family 2 member 1)
EnsemblGeneIds (GRCh38): ENSG00000117394
EnsemblGeneIds (GRCh37): ENSG00000117394
OMIM: 138140, Gene2Phenotype
SLC2A1 is in 25 panels

1 review

Ivone Leong (Genomics England Curator)

I don't know

GLUT1 is a receptor for HTLV and suggested that perturbations in glucose metabolism resulting from interactions of HTLV envelope glycoproteins with GLUT1 are likely to contribute to HTLV-associated disorders (PMID: 15767416).

PMID: 22308487 shows that IL-7 induced upregulation of Glut1 changes glucos uptake and causes T lymphocyptes susceptible to HIV-1 infection.
Sources: Expert list
Created: 26 May 2020, 10:13 a.m.

Mode of inheritance


History Filter Activity

26 May 2020, Gel status: 2

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: slc2a1 has been classified as Amber List (Moderate Evidence).

26 May 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications

Ivone Leong (Genomics England Curator)

gene: SLC2A1 was added gene: SLC2A1 was added to COVID-19 research. Sources: Expert list Mode of inheritance for gene: SLC2A1 was set to Unknown Publications for gene: SLC2A1 were set to 15767416; 22308487 Review for gene: SLC2A1 was set to AMBER