Genes in panel
STRs in panel
Prev Next

COVID-19 research

Gene: NRP2

Red List (low evidence)

NRP2 (neuropilin 2)
EnsemblGeneIds (GRCh38): ENSG00000118257
EnsemblGeneIds (GRCh37): ENSG00000118257
OMIM: 602070, Gene2Phenotype
NRP2 is in 2 panels

1 review

Eleanor Williams (Genomics England Curator)

Red List (low evidence)

Not associated with a disease phenotype in OMIM or Gene2Phenotype.

PMID: 30057110: Martinez-Martin et al. (2018) identified NRP2 as a host receptor for human cytomegalovirus (HCMV) pentamer.

PMID: 29120745 -Raaben et al 2017 - A genome-wide haploid genetic screen identified the transmembrane protein neuropilin 2 (NRP2) and tetraspanin CD63 as factors for Lujo virus (LUJV) glycoprotein-mediated infection. Overexpression of NRP2 or its N-terminal domain enhances VSV-LUJV infection, and cells lacking NRP2 are deficient in wild-type LUJV infection.
Sources: Literature
Created: 21 May 2020, 10:24 p.m.

Mode of inheritance



Mode of Inheritance
  • Literature
Clinvar variants
Variants in NRP2
Panels with this gene

History Filter Activity

21 May 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications

Eleanor Williams (Genomics England Curator)

gene: NRP2 was added gene: NRP2 was added to COVID-19 research. Sources: Literature Mode of inheritance for gene: NRP2 was set to Unknown Publications for gene: NRP2 were set to 30057110; 29120745 Review for gene: NRP2 was set to RED