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COVID-19 research

Gene: WSCD1

Red List (low evidence)

WSCD1 (WSC domain containing 1)
EnsemblGeneIds (GRCh38): ENSG00000179314
EnsemblGeneIds (GRCh37): ENSG00000179314
WSCD1 is in 1 panel

1 review

Sarah Leigh (Genomics England Curator)

Red List (low evidence)

Using Collaborative Cross mouse genetic reference population, PMID 32348764 studied the genetic regulation of variation in antibody response to influenza A virus (IAV) infection. This enabled the identification of 23 quantitative trait loci (QTL) associated with variation in specific antibody isotypes across time points; this allowed a subset to be found that broadly affect the antibody response to IAV as well as other viruses. This gene is the equivalent human for the mouse gene that was classified as a candidate from one of the QTLs, based on the predicted variant consequences and haplotype-specific expression patterns (PMID 32348764 table 2).
Created: 27 May 2020, 10:50 a.m. | Last Modified: 27 May 2020, 10:50 a.m.
Panel Version: 0.332

Mode of inheritance

Influenza A Virus-Specific Antibody Responses



  • Literature
Clinvar variants
Variants in WSCD1
Panels with this gene

History Filter Activity

5 May 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance

Sarah Leigh (Genomics England Curator)

gene: WSCD1 was added gene: WSCD1 was added to Viral susceptibility. Sources: Literature Mode of inheritance for gene: WSCD1 was set to