Genes in panel
STRs in panel
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COVID-19 research

Gene: STAT4

Red List (low evidence)

STAT4 (signal transducer and activator of transcription 4)
EnsemblGeneIds (GRCh38): ENSG00000138378
EnsemblGeneIds (GRCh37): ENSG00000138378
OMIM: 600558, Gene2Phenotype
STAT4 is in 2 panels

1 review

Louise Daugherty (Genomics England Curator)

Red List (low evidence)

Potential risk allele for SLE. New gene added after review of potential new genes for PID by the Immunology Test Group. This gene was noted as being only theoretical for PID so was rated as Red by the group.
Created: 27 Sep 2019, 2:54 p.m. | Last Modified: 27 Sep 2019, 2:54 p.m.
Panel Version: 1.132

Details

Mode of Inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
Phenotypes
  • {Systemic lupus erythematosus, susceptibility to, 11}, 612253
OMIM
600558
Clinvar variants
Variants in STAT4
Penetrance
None
Panels with this gene

History Filter Activity

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: STAT4 was added gene: STAT4 was added to Viral susceptibility. Sources: Expert Review Red,NHS GMS,London North GLH Mode of inheritance for gene: STAT4 was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal Phenotypes for gene: STAT4 were set to {Systemic lupus erythematosus, susceptibility to, 11}, 612253