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STRs in panel
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COVID-19 research

Gene: GAD1

Red List (low evidence)

GAD1 (glutamate decarboxylase 1)
EnsemblGeneIds (GRCh38): ENSG00000128683
EnsemblGeneIds (GRCh37): ENSG00000128683
OMIM: 605363, Gene2Phenotype
GAD1 is in 10 panels

6 reviews

Catherine Snow (Genomics England)

Comment on list classification: GAD1 has no relationship to virus susceptibility.
Created: 6 Apr 2020, 5:24 p.m. | Last Modified: 6 Apr 2020, 5:24 p.m.
Panel Version: 0.54

Louise Daugherty (Genomics England Curator)

Comment on phenotypes: removed 'Immunoglobulin A deficiency, 2' from the phenotype, there is no evidence to support this phenotype for this gene or where this assertion came from
Created: 26 Apr 2018, 9:26 a.m.

Tracy Briggs (Manchester Genomic Medicine Centre)

Red List (low evidence)

Peter Arkwright (Royal Manchester Foundation Trust)

Red List (low evidence)

Sarah Leigh (Genomics England Curator)

Comment when marking as ready: No evidence for association with A- or hypo-gammaglobulinaemia
Created: 11 May 2016, 9:44 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Sophie Hambleton (Newcastle University)

Red List (low evidence)

This gene appears to have no relationship to immunodeficiency
Created: 19 Oct 2015, 12:49 p.m.


Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
  • Expert Review Red
  • A- or hypo-gammaglobulinaemia v1.25
  • A- or hypo-gammaglobulinaemia v1.25
  • ?Cerebral palsy, spastic quadriplegic, 1, 603513
Clinvar variants
Variants in GAD1
Panels with this gene

History Filter Activity

6 Apr 2020, Gel status: 1

Entity classified by Genomics England curator

Catherine Snow (Genomics England)

Gene: gad1 has been classified as Red List (Low Evidence).

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: GAD1 was added gene: GAD1 was added to Viral susceptibility. Sources: Expert Review Red,A- or hypo-gammaglobulinaemia v1.25 Mode of inheritance for gene: GAD1 was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: GAD1 were set to ?Cerebral palsy, spastic quadriplegic, 1, 603513