Genes in panel
STRs in panel
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COVID-19 research

Gene: FBF1

Red List (low evidence)

FBF1 (Fas binding factor 1)
EnsemblGeneIds (GRCh38): ENSG00000188878
EnsemblGeneIds (GRCh37): ENSG00000188878
OMIM: 616807, Gene2Phenotype
FBF1 is in 2 panels

3 reviews

Catherine Snow (Genomics England)

Red List (low evidence)

No gene disease association can currently be found.
Created: 2 Apr 2020, 2:06 p.m. | Last Modified: 2 Apr 2020, 2:06 p.m.
Panel Version: 0.39

Sophie Hambleton (Newcastle University)

Red List (low evidence)

Louise Daugherty (Genomics England Curator)

Comment on list classification: Changed from Amber to Red, no published cases of immunodeficiency to date. Red review from external expert review. Referred back to Victorian Clinical Genetics Services for evidences.
Created: 3 Jul 2018, 12:24 p.m.
Comment on list classification: This gene was absent from the original PanelApp PID panel dataset (review April 2018). However it was listed in external expert immunodeficiency diagnostic gene list from Victorian Clinical Genetics Services. In this combined PID panel, this gene has been rated as AMBER and needs further curational review to assess pertinence prior to v1. No disorder or MOI was listed in the submitted list.
Created: 26 Jun 2018, 12:46 p.m.

Details

Mode of Inheritance
Unknown
Sources
OMIM
616807
Clinvar variants
Variants in FBF1
Penetrance
None
Panels with this gene

History Filter Activity

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance

Ellen McDonagh (Genomics England Curator)

gene: FBF1 was added gene: FBF1 was added to Viral susceptibility. Sources: Expert Review Red,Victorian Clinical Genetics Services Mode of inheritance for gene: FBF1 was set to Unknown