TNFAIP3

TNF alpha induced protein 3
OMIM: 191163, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels
Amber TNFAIP3 in Periodic fever syndromes

Level 3: Multi-system inflammatory/autoimmune disorders
Level 2: Rheumatological disorders
Version 1.33

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • Autoinflammatory syndrome, familial, Behcet-like, OMIM:616744
Red TNFAIP3 in Familial Meniere Disease

Level 3: Other hearing and ear disorders
Level 2: Hearing and ear disorders
Version 1.3

review Not set
Sources
  • Literature
Green TNFAIP3 in COVID-19 research


Level 2: Viral research
Version 1.141

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • IUIS Classification February 2018
  • London North GLH
  • NHS GMS
  • Victorian Clinical Genetics Services
  • North West GLH
  • ESID Registry 20171117
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
Phenotypes
  • Autoinflammatory syndrome, familial, Behcet-like, OMIM:616744
  • Autoimmune lymphoproliferative syndrome
  • Arthralgia, mucosal ulcers, ocular inflammation
Green TNFAIP3 in Primary immunodeficiency or monogenic inflammatory bowel disease


Version 4.191
Latest signed off version: v4.0 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Other
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
Phenotypes
  • Autoinflammatory syndrome, familial, Behcet-like, OMIM:616744
  • Autoimmune lymphoproliferative syndrome
  • Arthralgia, mucosal ulcers, ocular inflammation
Green TNFAIP3 in Severe Paediatric Disorders


Version 1.182

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Autoinflammatory syndrome, familial, Behcet-like, OMIM:616744
Green TNFAIP3 in Autoinflammatory disorders

Level 3: Primary immunodeficiency disorders
Level 2: Haematological disorders
Version 1.11
Latest signed off version: v1.0 (30 Nov 2022)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • NHS GMS
  • Expert Review Green
Phenotypes
  • Autoinflammatory syndrome, familial, Behcet-like, OMIM:616744