TNNI3

troponin I3, cardiac type
OMIM: 191044, Gene2Phenotype

7 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 7 panels
Red TNNI3 in Left Ventricular Noncompaction Cardiomyopathy Level 3: Cardiomyopathy Level 2: Cardiovascular disorders Version 1.4	review	Not set	Sources Expert Review Red Eligibility statement prior genetic testing Phenotypes Hypertrophic cardiomyopathy
Green TNNI3 in Hypertrophic cardiomyopathy Level 3: Cardiomyopathy Level 2: Cardiovascular disorders Version 4.7 Latest signed off version: v4.0 (22 Mar 2023) Component of the following Super Panels: Sudden unexplained death or survivors of a cardiac event	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources South West GLH London South GLH North West GLH Expert Review Green Eligibility statement prior genetic testing Expert list Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Emory Genetics Laboratory UKGTN Phenotypes Cardiomyopathy, familial hypertrophic, 7 ?Cardiomyopathy, dilated, 2A (611880) Cardiomyopathy, dilated, 1FF (613286) Cardiomyopathy, familial restrictive, 1 (115210) Cardiomyopathy, hypertrophic, 7 (613690)
Green TNNI3 in Dilated Cardiomyopathy and conduction defects Level 3: Cardiomyopathy Level 2: Cardiovascular disorders Version 1.85	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources South West GLH London South GLH North West GLH Expert Review Green UKGTN Expert list Emory Genetics Laboratory Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Phenotypes Cardiomyopathy, dilated, 1FF (613286) Cardiomyopathy, dilated, 1FF Cardiomyopathy, dilated, 2A, Cardiomyopathy, familial restrictive, 1 (115210) Cardiomyopathy, hypertrophic, 7 (613690) ?Cardiomyopathy, dilated, 2A (611880)
Green TNNI3 in Dilated and arrhythmogenic cardiomyopathy Level 3: Cardiomyopathy Level 2: Cardiovascular disorders Version 2.22 Latest signed off version: v2.8 (22 Mar 2023) Component of the following Super Panels: Sudden unexplained death or survivors of a cardiac event	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green UKGTN South West GLH Radboud University Medical Center, Nijmegen Illumina TruGenome Clinical Sequencing Services London South GLH North West GLH Expert list Emory Genetics Laboratory South West GLH London South GLH North West GLH Phenotypes Cardiomyopathy, dilated, 1FF (613286) Cardiomyopathy, dilated, 2A, ?Cardiomyopathy, dilated, 2A (611880) Cardiomyopathy, familial restrictive, 1 (115210) Cardiomyopathy, dilated, 1FF Cardiomyopathy, hypertrophic, 7 (613690)
Red TNNI3 in Hereditary neuropathy Level 3: Motor and Sensory Disorders of the PNS Level 2: Neurology and neurodevelopmental disorders Version 1.477	review	Not set	Sources NHS GMS South West GLH Emory Genetics Laboratory Phenotypes Cardiomyopathy
Green TNNI3 in Paediatric or syndromic cardiomyopathy Version 3.46 Latest signed off version: v3.0 (22 Mar 2023) Component of the following Super Panels: Unexplained death in infancy and sudden unexplained death in childhood	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources NHS GMS South West GLH London South GLH Expert Review Green Phenotypes Hypertrophic cardiomyopathy Cardiomyopathy, familial hypertrophic, 7 Cardiomyopathy, dilated, 1FF Cardiomyopathy, dilated, 2A,
Red TNNI3 in Hereditary neuropathy or pain disorder Version 3.94 Latest signed off version: v3.24 (15 May 2023)	review	Not set	Sources NHS GMS South West GLH Emory Genetics Laboratory NHS GMS South West GLH Phenotypes Cardiomyopathy