1. Panels
  2. A- or hypo-gammaglobulinaemia
  3. UNG
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A- or hypo-gammaglobulinaemia

Gene: UNG

Amber List (moderate evidence)
UNG (uracil DNA glycosylase)
EnsemblGeneIds (GRCh38): ENSG00000076248
EnsemblGeneIds (GRCh37): ENSG00000076248
OMIM: 191525, Gene2Phenotype
UNG is in 2 panels

2 reviews

Olivia Niblock (Genomics England Curator)

Comment on list classification: Unable to access full literature paper at present, however abstract details three individuals with variants in this gene with Hyper-IgM syndrome (12958596)
Created: 15 Aug 2017, 1:07 p.m.
Created: 15 Aug 2017, 1:07 p.m.

Panel version: 1.18

Sophie Hambleton (Newcastle University)

Green List (high evidence)

OMIM:191525
Created: 6 Jan 2017, 3:52 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Hyper IgM syndrome with lymphoid hyperplasia

Publications

Created: 6 Jan 2017, 3:52 p.m.

Panel version: 1.5

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
Phenotypes
  • Hyper IgM syndrome with lymphoid hyperplasia
OMIM
191525
Clinvar variants
Variants in UNG
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

15 Aug 2017, Gel status: 2

Gene classified by Genomics England curator

Olivia Niblock (Genomics England Curator)

This gene has been classified as Amber List (Moderate Evidence).

6 Jan 2017, Gel status: 0

Created

Sophie Hambleton (Newcastle University)

UNG was created by shamblet

6 Jan 2017, Gel status: 0

Added New Source

Sophie Hambleton (Newcastle University)

UNG was added to A- or hypo-gammaglobulinaemiapanel. Sources: Expert Review