NOG inhibits postoperative resynostosis in a mouse suturectomy model (Cooper et al 2009). Duplicated in 2q35 duplication syndrome that is associated with CSS. No specific reports of NOG variants and CSS? On GeneDX CSS panel ; Review on behalf of Tracy Lester and Andrew Wilkie
Created: 5 Mar 2019, 11:33 a.m.
Tarsal-carpal coalition syndrome; Multiple synostosis syndrome; Stapes ankylosis with broad thumb and toes (Teunissen-Cremers syndrome); Symphalangism, proximal,; Brachydactyly type B2.
This gene was part of an initial gene list collated by Tracy Lester, Oxford Medical Genetics Laboratories, Oxford University Hospitals NHS Foundation Trust, February 2019 on behalf of the GMS Musculoskeletal Specialist Group; Gene symbol submitted: NOG; Suggested initial gene rating: red
Created: 5 Mar 2019, 11:21 a.m.
Added phenotypes Tarsal-carpal coalition syndrome; Stapes ankylosis with broad thumb and toes (Teunissen-Cremers syndrome); Brachydactyly type B2; Multiple synostosis syndrome; Symphalangism, proximal for gene: NOG
gene: NOG was added gene: NOG was added to Craniosynostosis. Sources: NHS GMS Mode of inheritance for gene: NOG was set to