SCID
Gene: LIG4
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
SCID with microcephaly and radiosensitivity
Comment on list classification: Agreement from 5 reviewers.Created: 20 May 2016, 2:06 p.m.
This gene has been classified as Green List (High Evidence).
Phenotypes for LIG4 were set to LIG4 syndrome, 606593{Multiple myeloma, resistance to}, 254500Severe combined immunodeficiency with sensitivity to ionizing radiation, 602450; Severe Combined Immunodeficiency with Sensitivity to IonizingRadiation; LIG4 syndrome, 606593{Multiple myeloma, resistance to}, 254500; Severe combined immunodeficiency with sensitivity to ionizing radiation, 602450; T-B- SCID; T-B+ SCID; SCID with microcephaly and radiosensitivity
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene LIG4 was changed to BIALLELIC, autosomal or pseudoautosomal
LIG4 was added to SCIDpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN
Model of inheritance for gene LIG4 was changed to BIALLELIC, autosomal or pseudoautosomal
LIG4 was added to SCIDpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN
Model of inheritance for gene LIG4 was changed to BIALLELIC, autosomal or pseudoautosomal
LIG4 was added to SCIDpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN
LIG4 was added to SCIDpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN