Structural basal ganglia disorders

Gene: FOXP2

Green List (high evidence)

FOXP2 (forkhead box P2)
EnsemblGeneIds (GRCh38): ENSG00000128573
EnsemblGeneIds (GRCh37): ENSG00000128573
OMIM: 605317, Gene2Phenotype
FOXP2 is in 9 panels

2 reviews

Sarah Leigh (Genomics England Curator)

Comment when marking as ready: Associated with phenotype in OMIM and as a probable G2P. At least 2 variants reported, together with supporting in vitro evidence.
Created: 16 Mar 2017, 1:26 p.m.

Manju Kurian (UCL-Institute of Child Health)

Green List (high evidence)

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Emory Genetics Laboratory
  • Radboud University Medical Center, Nijmegen
  • Illumina TruGenome Clinical Sequencing Services
Phenotypes
  • Speech-language disorder-1 602081
OMIM
605317
Clinvar variants
Variants in FOXP2
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

16 Mar 2017, Gel status: 4

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

promoted 16/03/2017

16 Mar 2017, Gel status: 4

Gene classified by Genomics England curator

Sarah Leigh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

16 Mar 2017, Gel status: 3

Set publications

Sarah Leigh (Genomics England Curator)

Publications for FOXP2 were set to 22434823; 15877281; 11586359

7 Sep 2016, Gel status: 3

Added New Source

Sarah Leigh (Genomics England Curator)

FOXP2 was added to Structural basal ganglia disorderspanel. Source: Emory Genetics Laboratory

7 Sep 2016, Gel status: 2

Added New Source

Sarah Leigh (Genomics England Curator)

FOXP2 was added to Structural basal ganglia disorderspanel. Source: Radboud University Medical Center, Nijmegen

7 Sep 2016, Gel status: 0

Created

Sarah Leigh (Genomics England Curator)

FOXP2 was created by sleigh

7 Sep 2016, Gel status: 1

Added New Source

Sarah Leigh (Genomics England Curator)

FOXP2 was added to Structural basal ganglia disorderspanel. Sources: Illumina TruGenome Clinical Sequencing Services