added new-gene-name tag
Created: 9 Dec 2016, 4:23 p.m.
New gene name - NECTIN3.
Created: 7 Dec 2016, 5:42 p.m.
Comment on list classification: Not yet enough evidence to be considered a green gene.
Created: 3 Jun 2016, 8:01 a.m.
Is on the Manchester congenital cataracts gene panel. Is not associated with a disease in G2P or OMIM.
Created: 29 Apr 2016, 1:47 p.m.
1 patient described with severe bilateral cataracts, has a translocation that results in decreased expression of PVRL3. PVRL3 knockout mice exhibit lens and ocular defects.
Created: 25 May 2016, 8:11 a.m.
Variants in this GENE are reported as part of current diagnostic practice
PVRL3 was changed to NECTIN3
new-gene-name was removed from PVRL3. Panel: Cataracts
Publications for PVRL3 were set to Lachke et al (2012) Hum Genet 131:235-250
This gene has been classified as Red List (Low Evidence).
This gene has been classified as Amber List (Moderate Evidence).
PVRL3 was added to Cataractspanel. Sources: UKGTN