Left Ventricular Noncompaction Cardiomyopathy
Gene: MYH7

MYH7 (myosin heavy chain 7)
EnsemblGeneIds (GRCh38): ENSG00000092054
EnsemblGeneIds (GRCh37): ENSG00000092054
OMIM: 160760, Gene2Phenotype
MYH7 is in 14 panels

2 reviews

Caroline Wright (Genomics England Curator)

Comment when marking as ready: Lots of evidence in cardiomyopathy
Created: 11 Feb 2016, 1:20 p.m.

Created: 11 Feb 2016, 1:20 p.m.

Panel version: 0.5

Oxford Medical Genetics Laboratory (OUH NHS Foundation Trust)

Green List (high evidence)

Variants in this GENE are reported as part of current diagnostic practice

Created: 6 Jan 2016, 5:12 p.m.

Panel version: 0.0

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

Expert Review Green
Eligibility statement prior genetic testing
Expert list
Radboud University Medical Center, Nijmegen
Illumina TruGenome Clinical Sequencing Services

Phenotypes

Left ventricular noncompaction 5, OMIM:613426
Dilated cardiomyopathy 1S, MONDO:0013262

OMIM

160760

Clinvar variants

Variants in MYH7

Penetrance

Complete

Panels with this gene

History Filter Activity

2 Dec 2020, Gel status: 3

Set Phenotypes

Arina Puzriakova (Genomics England Curator)

Phenotypes for gene: MYH7 were changed from Left ventricular noncompaction 5 ; Hypertrophic cardiomyopathy to Left ventricular noncompaction 5, OMIM:613426; Dilated cardiomyopathy 1S, MONDO:0013262

11 Feb 2016, Gel status: 4

Gene classified by Genomics England curator

Caroline Wright (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

11 Feb 2016, Gel status: 4

Gene classified by Genomics England curator

Caroline Wright (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

12 Aug 2015, Gel status: 2