Haematological malignancies for rare disease
Gene: DOCK8
DOCK8 (dedicator of cytokinesis 8)
EnsemblGeneIds (GRCh38): ENSG00000107099
EnsemblGeneIds (GRCh37): ENSG00000107099
OMIM: 611432, Gene2Phenotype
DOCK8 is in 12 panels
EnsemblGeneIds (GRCh38): ENSG00000107099
EnsemblGeneIds (GRCh37): ENSG00000107099
OMIM: 611432, Gene2Phenotype
DOCK8 is in 12 panels
1 review
Clare Turnbull (Queen Mary University London)
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- Curated sources
- Expert Review Green
- Phenotypes
-
- Class: miscellaneous
- HyperIgE syndrome
- Squamous cell carcinoma
- Lymphoma
- OMIM
- 611432
- Clinvar variants
- Variants in DOCK8
- Penetrance
- None
- Panels with this gene
-
- Familial pulmonary fibrosis
- COVID-19 research
- Primary immunodeficiency or monogenic inflammatory bowel disease
- DDG2P
- Gastrointestinal epithelial barrier disorders
- Severe multi-system atopic disease with high IgE
- Infantile enterocolitis & monogenic inflammatory bowel disease
- Fetal anomalies
- Rare genetic inflammatory skin disorders
- Haematological malignancies for rare disease
- Haematological malignancies cancer susceptibility
- Intellectual disability
History Filter Activity
22 Aug 2018, Gel status: 4
Panel promoted to version 1.0
Ellen McDonagh (Genomics England Curator)22nd August 2018: Reviewed by Helen Brittain, and suggested changes approved by Clare Turnbull. Changes made prior to promoting to version 1.
10 Apr 2018, Gel status: 4
Added New Source
Ellen McDonagh (Genomics England Curator)DOCK8 was added to Haematological malignancies for rare disease panel. Sources: Expert Review Green,Curated sources
10 Apr 2018, Gel status: 4
Created
Ellen McDonagh (Genomics England Curator)DOCK8 was created by Ellen McDonagh