Haematological malignancies for rare disease

Gene: RAD51C

Amber List (moderate evidence)

RAD51C (RAD51 paralog C)
EnsemblGeneIds (GRCh38): ENSG00000108384
EnsemblGeneIds (GRCh37): ENSG00000108384
OMIM: 602774, Gene2Phenotype
RAD51C is in 22 panels

2 reviews

Ellen McDonagh (Genomics England Curator)

Comment on list classification: Demoted from Green to Amber as there is only one case reported to date. Confirmed with Clare Turnbull regarding this change.
Created: 22 Aug 2018, 8:02 a.m.

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

History Filter Activity

22 Aug 2018, Gel status: 2

Panel promoted to version 1.0

Ellen McDonagh (Genomics England Curator)

22nd August 2018: Reviewed by Helen Brittain, and suggested changes approved by Clare Turnbull. Changes made prior to promoting to version 1.

22 Aug 2018, Gel status: 2

Entity classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

Gene: rad51c has been classified as Amber List (Moderate Evidence).

10 Apr 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

RAD51C was added to Haematological malignancies for rare disease panel. Sources: Curated sources,Expert Review Green

10 Apr 2018, Gel status: 4

Created

Ellen McDonagh (Genomics England Curator)

RAD51C was created by Ellen McDonagh