Ectodermal dysplasiaGene: KRT25
Comment on list classification: Reviewed by member of Genomics England clinical team, suggested Green rating. Appropriate gene to phenotype in OMIM and reported in >3 families.
Created: 2 Dec 2019, 4:20 p.m. | Last Modified: 2 Dec 2019, 4:20 p.m.
Panel Version: 0.28
This gene was part of a gene list collated by John McGrath, KCL and Veronica Kinsler, UCL, 17.Jun.2019 on behalf of the GMS Skin Specialist Test Group. Gene Symbol submitted: KRT25; Suggested initial gene rating: Green; Evidence for inclusion: none provided; Evidence for exclusion: none provided; Technical notes (e.g. non-coding/CNV mutations requiring coverage?): none provided.
Created: 3 Sep 2019, 4:23 p.m. | Last Modified: 3 Sep 2019, 4:23 p.m.
Panel Version: 0.19
Publications for gene: KRT25 were set to
Gene: krt25 has been classified as Green List (High Evidence).
Phenotypes for gene: KRT25 were changed from to Woolly hair, autosomal recessive 3, 616760
gene: KRT25 was added gene: KRT25 was added to Ectodermal dysplasia. Sources: Expert Review Amber Mode of inheritance for gene: KRT25 was set to BIALLELIC, autosomal or pseudoautosomal