STRs in panel
Prev Next
Regions in panel
Prev Next

Severe multi-system atopic disease with high IgE

Gene: CARD11

Green List (high evidence)

CARD11 (caspase recruitment domain family member 11)
EnsemblGeneIds (GRCh38): ENSG00000198286
EnsemblGeneIds (GRCh37): ENSG00000198286
OMIM: 607210, Gene2Phenotype
CARD11 is in 4 panels

1 review

William Rae (University Hospital Southampton NHS Foundation Trust)

Green List (high evidence)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
multisystem atopic disease, eczema, raised IgE, low IgM, eosinophilia

Publications

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
Phenotypes
  • multisystem atopic disease, eczema, raised IgE, low IgM, eosinophilia
  • B-cell expansion with NFKB and T-cell anergy 616452 AD
OMIM
607210
Clinvar variants
Variants in CARD11
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

15 Aug 2017, Gel status: 4

Gene classified by Genomics England curator

Sarah Leigh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

15 Aug 2017, Gel status: 4

Gene classified by Genomics England curator

Sarah Leigh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

15 Aug 2017, Gel status: 0

Set Phenotypes

Sarah Leigh (Genomics England Curator)

Phenotypes for CARD11 were set to multisystem atopic disease, eczema, raised IgE, low IgM, eosinophilia; B-cell expansion with NFKB and T-cell anergy 616452 AD

15 Aug 2017, Gel status: 0

Set publications

Sarah Leigh (Genomics England Curator)

Publications for CARD11 were set to 28628108; 28747751

15 Aug 2017, Gel status: 0

Set publications

Sarah Leigh (Genomics England Curator)

Publications for CARD11 were set to 28628108

27 Jun 2017, Gel status: 0

Created

William Rae (University Hospital Southampton NHS Foundation Trust)

CARD11 was created by wmkr103

27 Jun 2017, Gel status: 0

Added New Source

William Rae (University Hospital Southampton NHS Foundation Trust)

CARD11 was added to Severe multi-system atopic disease with high IgEpanel. Sources: Literature