Inherited breast cancer and ovarian cancer
Gene: RAD51C

RAD51C (RAD51 paralog C)
EnsemblGeneIds (GRCh38): ENSG00000108384
EnsemblGeneIds (GRCh37): ENSG00000108384
OMIM: 602774, Gene2Phenotype
RAD51C is in 21 panels

1 review

Eleanor Williams (Genomics England Curator)

This gene has been added to the panel as it is listed in the NHS National Genomic Test Directory v4 for clinical indication R208 Inherited breast cancer and ovarian cancer.
Created: 12 Apr 2023, 1:47 p.m. | Last Modified: 12 Apr 2023, 1:47 p.m.

Panel Version: 2.3

Created: 12 Apr 2023, 1:47 p.m.
Last Modified: 12 Apr 2023, 1:47 p.m.
Panel version: 2.3

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

NHS GMS
Expert Review Green
Expert list

Phenotypes

{Breast-ovarian cancer, familial, susceptibility to, 3}, OMIM:613399

OMIM

602774

Clinvar variants

Variants in RAD51C

Penetrance

None

Panels with this gene

History Filter Activity

29 Jun 2023, Gel status: 3

Added New Source

Achchuthan Shanmugasundram (Genomics England Curator)

Source NHS GMS was added to RAD51C.

12 Apr 2023, Gel status: 3

Entity classified by Genomics England curator

Eleanor Williams (Genomics England Curator)

Gene: rad51c has been classified as Green List (High Evidence).

12 Apr 2023, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Eleanor Williams (Genomics England Curator)

gene: RAD51C was added gene: RAD51C was added to Inherited breast cancer and ovarian cancer. Sources: Expert list Mode of inheritance for gene: RAD51C was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: RAD51C were set to {Breast-ovarian cancer, familial, susceptibility to, 3}, OMIM:613399

Inherited breast cancer and ovarian cancer Gene: RAD51C