Corneal dystrophiesGene: TCF4
TCF4 is associated with Corneal dystrophy in OMIM but not in Gene2Phenotype. There is enough evidence for this gene to be rated green on this panel. It should be noted that the CTG18.1 repeat expansion in the intronic region of TCF4 may be difficult to analyse due to technical difficulties with short-read WGS.
Sources: Expert list
Created: 31 Jul 2019, 10:43 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Corneal dystrophy, Fuchs endothelial, 3, 613267
Gene: tcf4 has been classified as Green List (High Evidence).
gene: TCF4 was added gene: TCF4 was added to Corneal dystrophies. Sources: Expert list STR tags were added to gene: TCF4. Mode of inheritance for gene: TCF4 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: TCF4 were set to 29526280; 26401622 Phenotypes for gene: TCF4 were set to Corneal dystrophy, Fuchs endothelial, 3, 613267 Review for gene: TCF4 was set to GREEN