Long QT syndrome
Gene: TECRL

TECRL (trans-2,3-enoyl-CoA reductase like)
EnsemblGeneIds (GRCh38): ENSG00000205678
EnsemblGeneIds (GRCh37): ENSG00000205678
OMIM: 617242, Gene2Phenotype
TECRL is in 2 panels

1 review

Ivone Leong (Genomics England Curator)

I don't know

Comment on list classification: Promoted from Red to Amber to match the gene rating suggested in my previous review.
Created: 28 Sep 2021, 9:41 a.m. | Last Modified: 28 Sep 2021, 9:41 a.m.

Panel Version: 2.23

New gene submitted on behalf of the GMS Cardiology specialist group. The group has agreed that this gene should be Amber on this panel.
Sources: NHS GMS
Created: 18 Nov 2019, 2:07 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Ventricular tachycardia, catecholaminergic polymorphic, 3, 614021

Created: 18 Nov 2019, 2:07 p.m.

Panel version: 1.43

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

Expert Review Amber
NHS GMS

Phenotypes

Ventricular tachycardia, catecholaminergic polymorphic, 3, 614021

OMIM

617242

Clinvar variants

Variants in TECRL

Penetrance

None

Panels with this gene

History Filter Activity

28 Sep 2021, Gel status: 2

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: tecrl has been classified as Amber List (Moderate Evidence).

18 Nov 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: TECRL was added gene: TECRL was added to Long QT syndrome. Sources: NHS GMS Mode of inheritance for gene: TECRL was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: TECRL were set to Ventricular tachycardia, catecholaminergic polymorphic, 3, 614021 Review for gene: TECRL was set to AMBER

Long QT syndrome Gene: TECRL