Long QT syndrome
Gene: ALG10
ALG10 OMIM:618355 is not associated with Short QT phenotype in OMIM or in Gen2Phen. However, ALG10B OMIM:603313 is associated with Long QT syndrome, acquired, reduced susceptibility to OMIM:613688 (PMID:15280551). ALG10 was added to this panel in error.Created: 28 Oct 2021, 2:13 p.m. | Last Modified: 28 Oct 2021, 2:13 p.m.
Panel Version: 2.26
{Long QT syndrome, acquired, reduced susceptibility to} (OMIM 613688)Created: 25 Mar 2019, 4:30 p.m.
No evidence for this gene to include. PMID:15280551Created: 25 Mar 2019, 4:27 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Not on the Inherited Cardiac Condition Genes panel reported in: Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition Genes, Pua et al, Journal of Cardiovascular Translational Research, online Feb 2016 (doi:10.1007/s12265-016-9673-5). The panel contains disease-causing, putatively pathogenic, research and phenocopy genes.Created: 19 Feb 2016, 11:07 a.m.
this is a modifier gene not a LQT disease associated geneCreated: 2 Dec 2015, 5 p.m.
Publications
Mode of inheritance for gene: ALG10 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: ALG10 were set to 15280551
Phenotypes for gene: ALG10 were changed from {Acquired long QT syndrome, reduced susceptibility to}, 613688 to Progressive myoclonus epilepsy; CDG
Tag new-gene-name was removed from gene: ALG10.
Publications for gene: ALG10 were set to
Tag new-gene-name tag was added to gene: ALG10.
Source South West GLH was added to ALG10. Mode of inheritance for gene ALG10 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
ALG10 was added to Long QT syndromepanel. Sources: Radboud University Medical Center, Nijmegen