Refuted genes
Gene: RAD51C

RAD51C (RAD51 paralog C)
EnsemblGeneIds (GRCh38): ENSG00000108384
EnsemblGeneIds (GRCh37): ENSG00000108384
OMIM: 602774, Gene2Phenotype
RAD51C is in 21 panels

1 review

Rebecca Foulger (Genomics England curator)

RAD51C was green on the non-Fanconi anaemia panel. Based on re-evaluation of evidence, changed rating from Green to Amber on the non-FA panel, and any other live panels where biallelic MOI was recorded alongside the FA phenotype: Only 1 reported (biallelic) case supporting the FA phenotype.
Created: 1 Aug 2017, 1:41 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Fanconi anemia, complementation group O, 613390

Created: 1 Aug 2017, 1:41 p.m.

Panel version: 0.7

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

Other

Phenotypes

Fanconi anemia, complementation group O, 613390

OMIM

602774

Clinvar variants

Variants in RAD51C

Penetrance

Complete

Panels with this gene

History Filter Activity

1 Aug 2017, Gel status: 0

Added New Source

Rebecca Foulger (Genomics England curator)

RAD51C was added to Refuted genespanel. Sources: Other

1 Aug 2017, Gel status: 0

Created