Parathyroid Cancer
Gene: CDC73

CDC73 (cell division cycle 73)
EnsemblGeneIds (GRCh38): ENSG00000134371
EnsemblGeneIds (GRCh37): ENSG00000134371
OMIM: 607393, Gene2Phenotype
CDC73 is in 9 panels

2 reviews

Katie Snape (South London GMC)

Green List (high evidence)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Created: 5 Nov 2017, 2:40 a.m.

Panel version: 0

Louise IZATT (GSTT Clinical Genetics Service)

Green List (high evidence)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Created: 5 Nov 2017, 2:40 a.m.

Panel version: 0

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Sources

Expert Review Green
Eligibility statement prior genetic testing
Expert list
UKGTN
Illumina TruGenome Clinical Sequencing Services
Radboud University Medical Center, Nijmegen

Phenotypes

Hyperparathyroidism, familial primary, 145000
Hyperparathyroidism-jaw tumor syndrome, 145001
Parathyroid adenoma with cystic changes, 145001
Parathyroid carcinoma, 608266
Parathyroid Carcinoma
Pituitary Cancer, Parathyroid and Hypercalcemia
Parathyroid Cancer

OMIM

607393

Clinvar variants

Variants in CDC73

Penetrance

Complete

Panels with this gene

History Filter Activity

14 Feb 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

14 Feb 2016, Gel status: 3

Set Mode of Inheritance

Ellen Thomas (Genomics England Curator)

Mode of inheritance for CDC73 was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

18 Aug 2015, Gel status: 3