Segmental overgrowth disorders - Deep sequencing
Gene: KRAS
KRAS (KRAS proto-oncogene, GTPase)
EnsemblGeneIds (GRCh38): ENSG00000133703
EnsemblGeneIds (GRCh37): ENSG00000133703
OMIM: 190070, Gene2Phenotype
KRAS is in 30 panels
EnsemblGeneIds (GRCh38): ENSG00000133703
EnsemblGeneIds (GRCh37): ENSG00000133703
OMIM: 190070, Gene2Phenotype
KRAS is in 30 panels
0 reviews
Details
- Sources
-
- Other
- Phenotypes
-
- Hemimegalencephaly
- Schimmelpenning-Feuerstein-Mims syndrome, somatic mosaic, 163200
- OMIM
- 190070
- Clinvar variants
- Variants in KRAS
- Penetrance
- Complete
- Panels with this gene
-
- Early onset or syndromic epilepsy
- Primary immunodeficiency or monogenic inflammatory bowel disease
- Pigmentary skin disorders
- Fetal hydrops
- Paediatric or syndromic cardiomyopathy
- Familial rhabdomyosarcoma
- Segmental overgrowth disorders - Deep sequencing
- Intellectual disability
- Embryonal tumour of possible germline origin
- RASopathies
- IUGR and IGF abnormalities
- Mosaic skin disorders - deep sequencing
- DDG2P
- Hereditary neuropathy
- Fetal anomalies
- Childhood solid tumours cancer susceptibility
- Cytopenias and congenital anaemias
- Rare syndromic craniosynostosis or isolated multisuture synostosis
- Multiple monogenic benign skin tumours
- Sarcoma cancer susceptibility
- COVID-19 research
- Monogenic short stature
- Childhood solid tumours
- Sarcoma susceptibility
- Osteogenesis imperfecta
- Adult solid tumours cancer susceptibility
- Primary lymphoedema
- Hereditary neuropathy or pain disorder
- Sarcoma of possible germline origin
- Neurological segmental overgrowth
History Filter Activity
28 Nov 2016, Gel status: 0
panel promoted to version 1
Rebecca Foulger (Genomics England curator)28 November 2016: Reviews were assessed, and panel was revised according to expert review and additional curation.
7 Nov 2016, Gel status: 0
Created
Rebecca Foulger (Genomics England curator)KRAS was created by rfoulger
7 Nov 2016, Gel status: 0
Added New Source
Rebecca Foulger (Genomics England curator)KRAS was added to Regional overgrowth disorderspanel. Sources: Other