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Likely inborn error of metabolism v8.94 COX11 Achchuthan Shanmugasundram Tag Q2_25_ promote_green was removed from gene: COX11.
Likely inborn error of metabolism v8.94 COX11 Achchuthan Shanmugasundram commented on gene: COX11: The rating of this gene has been updated to green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.
Likely inborn error of metabolism v8.93 COX11 Achchuthan Shanmugasundram Source Expert Review Green was added to COX11.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Likely inborn error of metabolism v8.17 COX11 Achchuthan Shanmugasundram edited their review of gene: COX11: Changed rating: GREEN; Changed mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Likely inborn error of metabolism v8.17 COX11 Achchuthan Shanmugasundram changed review comment from: Comment on list classification: This gene should be added with green rating to this panel as this gene has already been promoted to green rating on Mitochondrial disorders panel (https://panelapp.genomicsengland.co.uk/panels/112/gene/C2orf69/).; to: Comment on list classification: This gene should be added with green rating to this panel as this gene has already been promoted to green rating on Mitochondrial disorders panel (https://panelapp.genomicsengland.co.uk/panels/112/gene/COX11/).
Likely inborn error of metabolism v8.17 COX11 Achchuthan Shanmugasundram Classified gene: COX11 as Amber List (moderate evidence)
Likely inborn error of metabolism v8.17 COX11 Achchuthan Shanmugasundram Added comment: Comment on list classification: This gene should be added with green rating to this panel as this gene has already been promoted to green rating on Mitochondrial disorders panel (https://panelapp.genomicsengland.co.uk/panels/112/gene/C2orf69/).
Likely inborn error of metabolism v8.17 COX11 Achchuthan Shanmugasundram Gene: cox11 has been classified as Amber List (Moderate Evidence).
Likely inborn error of metabolism v8.16 COX11 Achchuthan Shanmugasundram Tag Q2_25_ promote_green tag was added to gene: COX11.
Likely inborn error of metabolism v8.16 COX11 Achchuthan Shanmugasundram Entity copied from Mitochondrial disorders v9.15
Likely inborn error of metabolism v8.16 COX11 Achchuthan Shanmugasundram gene: COX11 was added
gene: COX11 was added to Likely inborn error of metabolism. Sources: Expert Review Green,NHS GMS
Mode of inheritance for gene: COX11 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: COX11 were set to 36030551; 38068960
Phenotypes for gene: COX11 were set to Mitochondrial complex IV deficiency, nuclear type 23, OMIM:620275; Mitochondrial complex IV deficiency, nuclear type 23, MONDO:0859520