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Optic neuropathy v5.28 MT-ND5 Ida Ertmanska Tag technical-limitations tag was added to gene: MT-ND5.
Optic neuropathy v5.28 MT-ND5 Ida Ertmanska Tag Q2_25_ promote_green was removed from gene: MT-ND5.
Tag Q2_25_expert_review was removed from gene: MT-ND5.
Tag Q2_25_ NHS_review was removed from gene: MT-ND5.
Optic neuropathy v5.28 MT-ND5 Ida Ertmanska commented on gene: MT-ND5
Optic neuropathy v5.18 MT-ND5 Achchuthan Shanmugasundram Classified gene: MT-ND5 as Amber List (moderate evidence)
Optic neuropathy v5.18 MT-ND5 Achchuthan Shanmugasundram Added comment: Comment on list classification: As reviewed by Katherine Schon, there is sufficient evidence available for the association of MT-ND5 gene with LHON. Hence, this gene can be promoted to green rating in the next GMS update.
Optic neuropathy v5.18 MT-ND5 Achchuthan Shanmugasundram Gene: mt-nd5 has been classified as Amber List (Moderate Evidence).
Optic neuropathy v5.17 MT-ND5 Achchuthan Shanmugasundram Tag Q2_25_ promote_green tag was added to gene: MT-ND5.
Tag Q2_25_expert_review tag was added to gene: MT-ND5.
Tag Q2_25_ NHS_review tag was added to gene: MT-ND5.
Optic neuropathy v5.17 MT-ND5 Achchuthan Shanmugasundram Phenotypes for gene: MT-ND5 were changed from to Leber hereditary optic neuropathy, MONDO:0010788
Optic neuropathy v5.16 MT-ND5 Achchuthan Shanmugasundram Publications for gene: MT-ND5 were set to
Optic neuropathy v5.15 MT-ND5 Achchuthan Shanmugasundram reviewed gene: MT-ND5: Rating: GREEN; Mode of pathogenicity: None; Publications: 12509858, 12736867, 27164671, 38357617; Phenotypes: Leber hereditary optic neuropathy, MONDO:0010788; Mode of inheritance: MITOCHONDRIAL
Optic neuropathy v5.3 MT-ND5 Katherine Schon reviewed gene: MT-ND5: Rating: GREEN; Mode of pathogenicity: ; Publications: 27164671, 12736867, 38357617; Phenotypes: ; Mode of inheritance: MITOCHONDRIAL
Optic neuropathy v5.2 MT-ND5 Achchuthan Shanmugasundram gene: MT-ND5 was added
gene: MT-ND5 was added to Optic neuropathy. Sources: Literature
Mode of inheritance for gene gene: MT-ND5 was set to MITOCHONDRIAL