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Cholestasis v0.21 NR1H4 Ivone Leong Marked gene: NR1H4 as ready
Cholestasis v0.21 NR1H4 Ivone Leong Added comment: Comment when marking as ready: As discussed in the GMS Gastrohepatology Specialist Test Group webex call 14th Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green.
Cholestasis v0.21 NR1H4 Ivone Leong Gene: nr1h4 has been classified as Green List (High Evidence).
Cholestasis v0.10 NR1H4 Ivone Leong Source Other was added to NR1H4.
Mode of inheritance for gene NR1H4 was changed from to BIALLELIC, autosomal or pseudoautosomal
Added phenotypes ciliopathy; modifier of other genetic cholestatic conditions; Cholestasis, Progressive Familial Intrahepatic 5; Cholestasis, progressive familial intrahepatic 5, 617049; Neonatal and Adult Cholestasis for gene: NR1H4
Cholestasis v0.4 NR1H4 Ivone Leong Source Expert Review Green was added to NR1H4.
Rating Changed from Red List (low evidence) to Green List (high evidence)
Cholestasis v0.3 NR1H4 Ivone Leong reviewed gene: NR1H4: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Cholestasis v0.2 NR1H4 Ivone Leong gene: NR1H4 was added
gene: NR1H4 was added to Cholestasis. Sources: NHS GMS
Mode of inheritance for gene: NR1H4 was set to