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Likely inborn error of metabolism v8.94 QARS Achchuthan Shanmugasundram Tag Q2_25_ promote_green was removed from gene: QARS.
Likely inborn error of metabolism v8.94 QARS Achchuthan Shanmugasundram commented on gene: QARS: The rating of this gene has been updated to green following NHS Genomic Medicine Service approval.
Likely inborn error of metabolism v8.93 QARS Achchuthan Shanmugasundram Source NHS GMS was added to QARS.
Source Expert Review Green was added to QARS.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Likely inborn error of metabolism v8.42 QARS Achchuthan Shanmugasundram Classified gene: QARS as Amber List (moderate evidence)
Likely inborn error of metabolism v8.42 QARS Achchuthan Shanmugasundram Added comment: Comment on list classification: QARS has already been promoted to green rating on Mitochondrial disorders panel (https://panelapp.genomicsengland.co.uk/panels/112/gene/QARS/). Hence, this gene can also be promoted to green rating on this panel in the next GMS update.
Likely inborn error of metabolism v8.42 QARS Achchuthan Shanmugasundram Gene: qars has been classified as Amber List (Moderate Evidence).
Likely inborn error of metabolism v8.41 QARS Achchuthan Shanmugasundram Phenotypes for gene: QARS were changed from Multiple respiratory chain complex deficiencies (disorders of protein synthesis) to Microcephaly, progressive, seizures, and cerebral and cerebellar atrophy, OMIM:615760
Likely inborn error of metabolism v8.40 QARS Achchuthan Shanmugasundram Publications for gene: QARS were set to 28620870; 25471517; 25432320; 25041233; 24656866
Likely inborn error of metabolism v8.39 QARS Achchuthan Shanmugasundram Tag Q2_25_ promote_green tag was added to gene: QARS.
Likely inborn error of metabolism v8.39 QARS Achchuthan Shanmugasundram reviewed gene: QARS: Rating: GREEN; Mode of pathogenicity: None; Publications: 32042906; Phenotypes: Microcephaly, progressive, seizures, and cerebral and cerebellar atrophy, OMIM:615760; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Likely inborn error of metabolism v2.234 QARS Sarah Leigh Mode of inheritance for gene: QARS was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal
Likely inborn error of metabolism v2.233 QARS Sarah Leigh Mode of inheritance for gene: QARS was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal
Likely inborn error of metabolism v2.233 QARS Sarah Leigh Publications for gene: QARS were set to
Likely inborn error of metabolism v1.262 QARS Louise Daugherty Tag new-gene-name tag was added to gene: QARS.
Likely inborn error of metabolism v1.262 QARS Louise Daugherty commented on gene: QARS
Likely inborn error of metabolism v0.4 QARS Ellen McDonagh gene: QARS was added
gene: QARS was added to Inborn errors of metabolism. Sources: Expert Review Amber
Mode of inheritance for gene: QARS was set to Unknown
Phenotypes for gene: QARS were set to Multiple respiratory chain complex deficiencies (disorders of protein synthesis)