ACE

angiotensin I converting enzyme
OMIM: 106180, Gene2Phenotype

9 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 9 panels
Red ACE in COVID-19 research Level 2: Viral research Version 1.146	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Red Literature Phenotypes Not associated with susceptibility to SARS-coronavirus infection and disease outcomes
Red ACE in Familial hypercholesterolaemia Level 3: Arteriopathies Level 2: Cardiovascular disorders Version 1.31	review	Not set	Sources Radboud University Medical Center, Nijmegen Phenotypes {Myocardial infarction, susceptibility to} {Alzheimer disease, susceptibility to}, 104300 {Microvascular complications of diabetes 3}, 612624 [Angiotensin I-converting enzyme, benign serum increase] {SARS, progression of} Renal tubular
Red ACE in Cerebral vascular malformations Level 2: Neurology Version 4.10 Latest signed off version: v4.0 (30 Apr 2025)	review	Not set	Sources Yorkshire and North East GLH NHS GMS Expert Review Red Other Phenotypes {Stroke, hemorrhagic}
No list ACE in Diabetes with additional phenotypes suggestive of a monogenic aetiology Level 3: Disorders of unusual phenotypes Level 2: Endocrine disorders Version 1.68	review	Not set	Sources Expert Review Removed Radboud University Medical Center, Nijmegen Phenotypes {Myocardial infarction, susceptibility to} {Alzheimer disease, susceptibility to}, 104300 {Microvascular complications of diabetes 3}, 612624 [Angiotensin I-converting enzyme, benign serum increase] {SARS, progression of} Renal tubular Tags curated_removed
Green ACE in Unexplained kidney failure in young people Level 3: Disorders of function Level 2: Renal and urinary tract disorders Version 1.124	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green UKGTN Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Phenotypes Renal Tubular Dysgenesis 267430
Green ACE in CAKUT Level 3: Structural renal and urinary tract disease Level 2: Renal and urinary tract disorders Version 1.181	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Radboud University Medical Center, Nijmegen Illumina TruGenome Clinical Sequencing Services Phenotypes Renal Tubular Dysgenesis {Myocardial infarction, susceptibility to}{Alzheimer disease, susceptibility to}, 104300{Microvascular complications of diabetes 3}, 612624[Angiotensin I-converting enzyme, benign serum increase]{SARS, progression of}Renal tubular
Green ACE in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources PAGE Additional Gene List Expert Review Green Phenotypes Renal tubular dysgenesis 267430
Green ACE in Paediatric disorders - additional genes Level 2: Developmental disorders Version 7.31 Latest signed off version: v7.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other Phenotypes CAKUT Renal Tubular Dysgenesis
Green ACE in Unexplained young onset end-stage renal disease - additional genes Level 2: Renal Version 1.4 Latest signed off version: v1.1 (30 Apr 2025) Component of the following Super Panels: Unexplained young onset end-stage renal disease	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes Renal tubular dysgenesis, OMIM:267430