APOL1

apolipoprotein L1
OMIM: 603743, Gene2Phenotype

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Green APOL1 in COVID-19 research Level 2: Viral research Version 1.146	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green IUIS Classification February 2018 IUIS Classification December 2019 GRID V2.0 Victorian Clinical Genetics Services ESID Registry 20171117 IUIS Classification December 2019 IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Phenotypes Trypanosomias Trypanosomiasis, susceptibility to Defects in Intrinsic and Innate Immunity Trypanosomiasis
Red APOL1 in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.78 Latest signed off version: v8.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources IUIS Classification December 2019 IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Red ESID Registry 20171117 GRID V2.0 Phenotypes Trypanosomias Trypanosomiasis Defects in Intrinsic and Innate Immunity Trypanosomiasis, susceptibility to
Red APOL1 in Unexplained kidney failure in young people Level 3: Disorders of function Level 2: Renal and urinary tract disorders Version 1.124	review	Not set	Sources Eligibility statement prior genetic testing
Amber APOL1 in Proteinuric renal disease Level 2: Renal Version 5.7 Latest signed off version: v5.0 (30 Apr 2025) Component of the following Super Panels: Unexplained young onset end-stage renal disease	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber NHS GMS Eligibility statement prior genetic testing Phenotypes {Focal Segmental Glomerulosclerosis 4, Susceptibility to} OMIM:612551 {End-stage renal disease, nondiabetic, susceptibility to} OMIM:612551
Green APOL1 in APOL1 kidney donor testing Level 2: Renal Version 1.2 Latest signed off version: v1.0 (30 Oct 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Phenotypes {Glomerulosclerosis, focal segmental, 4, susceptibility to}, OMIM:612551