APOL1

apolipoprotein L1
OMIM: 603743, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Green APOL1 in COVID-19 research Level 2: Viral research Version 1.141	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green IUIS Classification February 2018 IUIS Classification December 2019 GRID V2.0 Victorian Clinical Genetics Services ESID Registry 20171117 IUIS Classification December 2019 IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Phenotypes Trypanosomias Trypanosomiasis, susceptibility to Defects in Intrinsic and Innate Immunity Trypanosomiasis
Red APOL1 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.201 Latest signed off version: v4.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources IUIS Classification December 2019 IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Red ESID Registry 20171117 GRID V2.0 Phenotypes Trypanosomias Trypanosomiasis Defects in Intrinsic and Innate Immunity Trypanosomiasis, susceptibility to
Red APOL1 in Unexplained kidney failure in young people Level 3: Disorders of function Level 2: Renal and urinary tract disorders Version 1.118 Component of the following Super Panels: Renal superpanel - broad	review	Not set	Sources Eligibility statement prior genetic testing
Red APOL1 in Unexplained young onset end-stage renal disease Version 3.40 Latest signed off version: v3.0 (22 Mar 2023) Component of the following Super Panels: Renal superpanel - broad	review	Unknown	Sources Expert Review Red
Amber APOL1 in Proteinuric renal disease Level 3: Syndromes with prominent renal abnormalities Level 2: Renal and urinary tract disorders Version 4.12 Latest signed off version: v4.0 (22 Mar 2023) Component of the following Super Panels: Renal superpanel - broad Renal superpanel - narrow	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber NHS GMS Eligibility statement prior genetic testing Phenotypes {Focal Segmental Glomerulosclerosis 4, Susceptibility to} OMIM:612551 {End-stage renal disease, nondiabetic, susceptibility to} OMIM:612551
Amber APOL1 in Severe Paediatric Disorders Version 1.184	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Next Generation Children Project Expert Review Amber Expert list Phenotypes {Glomerulosclerosis, focal segmental, 4, susceptibility to}, 612551 {End-stage renal disease, nondiabetic, susceptibility to}, 612551