Level 2: Viral research
Version 1.141
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review
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BIALLELIC, autosomal or pseudoautosomal
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Sources
- IUIS Classification February 2018
- London North GLH
- NHS GMS
- GRID V2.0
- North West GLH
- Victorian Clinical Genetics Services
- Expert Review Green
- NHS GMS
- North West GLH
- London North GLH
- IUIS Classification February 2018
- Victorian Clinical Genetics Services
- Expert Review Green
- GRID V2.0
Phenotypes
- Neurocognitive developmental aberrations, microcephaly, hypoglycemia, hypotonia, ataxia, seizures, cataracts, IUGR
- Congenital defects of phagocyte number or function
- 3-methylglutaconic aciduria, type VII, with cataracts, neurologic involvement and neutropenia, 616271
- 3-methylglutaconic aciduria, type VII
- 3-methylglutaconic aciduria, type 7
- Recurrent or severe infection
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Version 4.201
Latest signed off version: v4.0
(22 Mar 2023)
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review
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BOTH monoallelic and biallelic, autosomal or pseudoautosomal
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Sources
- NHS GMS
- North West GLH
- London North GLH
- IUIS Classification February 2018
- Victorian Clinical Genetics Services
- Expert Review Green
- GRID V2.0
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM: 619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM: 619813
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Version 3.32
Latest signed off version: v3.0
(22 Mar 2023)
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review
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BOTH monoallelic and biallelic, autosomal or pseudoautosomal
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Sources
- Expert Review Green
- Expert review Red
- NHS GMS
- North West GLH
- London South GLH
- Yorkshire and North East GLH
- Wessex and West Midlands GLH
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM:619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM:619813
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Level 3: Specific metabolic abnormalities
Level 2: Metabolic disorders
Version 1.617
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review
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BOTH monoallelic and biallelic, autosomal or pseudoautosomal
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Sources
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM: 619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM: 619813
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Version 4.137
Latest signed off version: v4.0
(22 Mar 2023)
Component of the following Super Panels:
Childhood onset leukodystrophy
Hypotonic infant
Paediatric disorders
Unexplained death in infancy and sudden unexplained death in childhood
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review
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BOTH monoallelic and biallelic, autosomal or pseudoautosomal
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Sources
- NHS GMS
- Expert Review Green
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM: 619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM: 619813
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Version 3.105
Latest signed off version: v3.0
(22 Mar 2023)
|
review
|
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
|
Sources
- NHS GMS
- Expert Review Green
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM: 619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM: 619813
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Version 3.155
Latest signed off version: v3.0
(22 Mar 2023)
|
review
|
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
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Sources
- NHS GMS
- PAGE DD-Gene2Phenotype
- Expert Review Green
Phenotypes
- 3-methylglutaconic aciduria, type VII, with cataracts, neurologic involvement and neutropenia, OMIM:616271
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Version 3.87
Latest signed off version: v3.1
(22 Mar 2023)
Component of the following Super Panels:
Paediatric disorders
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review
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BIALLELIC, autosomal or pseudoautosomal
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Sources
- DD-Gene2Phenotype
- Expert Review Green
Phenotypes
- 3-METHYLGLUTACONIC ACIDURIA, TYPE VII, WITH CATARACTS, NEUROLOGIC INVOLVEMENT AND NEUTROPENIA 616271
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Level 3: Inherited Epilepsy Syndromes
Level 2: Neurology and neurodevelopmental disorders
Version 4.193
Latest signed off version: v4.0
(22 Mar 2023)
Component of the following Super Panels:
Unexplained death in infancy and sudden unexplained death in childhood
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review
|
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
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Sources
- NHS GMS
- Expert Review Green
- Literature
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM:619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM:619813
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Level 3: Neurodevelopmental disorders
Level 2: Neurology and neurodevelopmental disorders
Version 5.531
Latest signed off version: v5.0
(22 Mar 2023)
Component of the following Super Panels:
Childhood onset leukodystrophy
Hypotonic infant
Paediatric disorders
|
review
|
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
|
Sources
- NHS GMS
- Victorian Clinical Genetics Services
- Expert Review Green
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM:619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM:619813
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Level 3: Mitochondrial
Level 2: Metabolic disorders
Version 4.168
Latest signed off version: v4.0
(22 Mar 2023)
Component of the following Super Panels:
Childhood onset leukodystrophy
|
review
|
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
|
Sources
- NHS GMS
- Victorian Clinical Genetics Services
- Expert Review Green
- Expert list
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM: 619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM: 619813
|
Version 3.75
Latest signed off version: v3.0
(22 Mar 2023)
|
review
|
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
|
Sources
- NHS GMS
- Expert Review Green
- London North GLH
Phenotypes
- 3-methylglutaconic aciduria, type VIIB, autosomal recessive, OMIM:616271
- 3-methylglutaconic aciduria, type VIIA, autosomal dominant, OMIM:619835
- Neutropenia, severe congenital, 9, autosomal dominant, OMIM:619813
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Version 1.184
|
review
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BIALLELIC, autosomal or pseudoautosomal
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Sources
- Next Generation Children Project
- Expert Review Green
- Expert list
Phenotypes
- 3-methylglutaconic aciduria, type VII, with cataracts, neurologic involvement and neutropenia, OMIM:616271
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