CYP11B2

cytochrome P450 family 11 subfamily B member 2
OMIM: 124080, Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Green CYP11B2 in Congenital adrenal hypoplasia Level 2: Endocrinology Version 4.11 Latest signed off version: v4.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Literature Phenotypes Hypoaldosteronism, congenital, due to CMO I deficiency, OMIM:203400 Hypoaldosteronism, congenital, due to CMO II deficiency, OMIM:610600 Aldosterone to renin ratio raised Tags treatable
Green CYP11B2 in Extreme early-onset hypertension Level 3: Disorders of function Level 2: Renal and urinary tract disorders Version 1.23	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Radboud University Medical Center, Nijmegen Phenotypes Aldosteronism, glucocorticoid-remediable, OMIM:103900 {Low renin hypertension, susceptibility to} Aldosterone to renin ratio raised Tags chimeric-gene
Red CYP11B2 in Unexplained kidney failure in young people Level 3: Disorders of function Level 2: Renal and urinary tract disorders Version 1.124	review	Not set	Sources Eligibility statement prior genetic testing
Red CYP11B2 in Proteinuric renal disease Level 2: Renal Version 5.7 Latest signed off version: v5.0 (30 Apr 2025) Component of the following Super Panels: Unexplained young onset end-stage renal disease	review	Not set	Sources NHS GMS Expert Review Red Eligibility statement prior genetic testing Phenotypes Hypoaldosteronism, congenital, due to CMO I deficiency #203400 Hypoaldosteronism, congenital, due to CMO II deficiency #610600