FLT4

fms related tyrosine kinase 4
OMIM: 136352, Gene2Phenotype

10 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 10 panels
Red FLT4 in PHACE(S) syndrome Level 3: Dysmorphic disorders Level 2: Dysmorphic and congenital abnormality syndromes Version 1.4	review	Not set	Sources Radboud University Medical Center, Nijmegen Phenotypes Hemangioma, capillary infantile, somatic, 602089
Green FLT4 in Fetal hydrops Level 3: Fetal disorders Level 2: Dysmorphic and congenital abnormality syndromes Version 1.95	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Other Literature Phenotypes Lymphedema, hereditary, IA, 153100 Hereditary lymphoedema type 1a fetal hydrops
Red FLT4 in Cerebral vascular malformations Level 2: Neurology Version 4.10 Latest signed off version: v4.0 (30 Apr 2025)	review	Not set	Sources Yorkshire and North East GLH NHS GMS Expert Review Red Other Radboud University Medical Center, Nijmegen Phenotypes Hemangioma, capillary infantile, somatic, 602089 Hemangioma, capillary infantile, somatic
Amber FLT4 in Rare genetic inflammatory skin disorders Level 2: Dermatology Version 4.16 Latest signed off version: v4.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber
Green FLT4 in Vascular skin disorders Level 2: Dermatology Version 2.5 Latest signed off version: v2.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green London North GLH NHS GMS Phenotypes Hemangioma, capillary infantile, somatic, OMIM:602089 Tags somatic to_be_confirmed_NHSE
Red FLT4 in Familial non syndromic congenital heart disease Level 3: Congenital heart disease Level 2: Cardiovascular disorders Version 1.90	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Literature Phenotypes Tetralogy of Fallot
Green FLT4 in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources PAGE DD-Gene2Phenotype Expert Review Green Phenotypes MILROY DISEASE
Green FLT4 in DDG2P Version 6.424 Latest signed off version: v6.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources DD-Gene2Phenotype Expert Review Green Phenotypes MILROY DISEASE 153100
Red FLT4 in Intellectual disability Level 2: Developmental disorders Version 9.285 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Red BRIDGE study SPEED NEURO Tier1 Gene Phenotypes Lymphedema, hereditary, IA, 153100 Hemangioma, capillary infantile, somatic, 602089
Green FLT4 in Primary lymphoedema Level 2: Cardiology Version 4.21 Latest signed off version: v4.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources London South GLH Eligibility statement prior genetic testing Radboud University Medical Center, Nijmegen UKGTN Expert Review Green Phenotypes Lymphedema, hereditary, IA 153100