Vascular skin disordersGene: FLT4
Main association is with lymphedema, somatic variants have been linked to haemangiomas ?single report.
Created: 2 Jul 2020, 4:11 a.m. | Last Modified: 2 Jul 2020, 4:11 a.m.
Panel Version: 1.3
Hemangioma, capillary infantile, somatic, MIM# 602089
This gene was part of an initial gene list collated by Thomas Cullup, GOSH and Veronica Kinsler, UCL, 25.Jan.2019 on behalf of the GMS Skin Specialist Test Group. Gene Symbol submitted: FLT4; Suggested initial gene rating: Green; Evidence for inclusion: none provided; Evidence for exclusion: none provided; Technical notes (e.g. non-coding/CNV mutations requiring coverage?): none provided.
Created: 31 Jan 2019, 12:05 p.m.
Variants in this GENE are reported as part of current diagnostic practice
Source London North GLH was added to FLT4.
gene: FLT4 was added gene: FLT4 was added to Vascular skin disorders. Sources: Expert Review Green,NHS GMS Mode of inheritance for gene: FLT4 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: FLT4 were set to Infantile haemangioma; Milroy disease