IL10

interleukin 10
OMIM: 124092, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Amber IL10 in Infantile enterocolitis & monogenic inflammatory bowel disease Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.45	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber UKGTN Eligibility statement prior genetic testing Expert list Phenotypes IL-10 signalling defects / deficiency IL10-Related Inflammatory Bowel Disease
Red IL10 in Familial Meniere Disease Level 3: Other hearing and ear disorders Level 2: Hearing and ear disorders Version 1.4	review	Not set	Sources Literature
Green IL10 in Gastrointestinal epithelial barrier disorders Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.76	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other UKGTN Phenotypes Inflammatory Bowel Disease (Very Early Onset) Crohn disease
Green IL10 in COVID-19 research Level 2: Viral research Version 1.146	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH GOSH PID v.8.0 NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes Early-onset inflammatory bowel disease Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome Inflammatory bowel disease (IBD) Folliculitis, recurrent respiratory diseases, arthritis, Diseases of Immune Dysregulation
No list IL10 in Sudden death in young people Level 3: Cardiac arrhythmia Level 2: Cardiovascular disorders Version 1.16	review	Unknown	Sources Expert Review Removed Literature Tags promoter curated_removed
Green IL10 in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.78 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes Early-onset inflammatory bowel disease Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome Inflammatory bowel disease (IBD) Folliculitis, recurrent respiratory diseases, arthritis, Diseases of Immune Dysregulation