MORC2

MORC family CW-type zinc finger 2
OMIM: 616661, Gene2Phenotype

9 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 9 panels
Green MORC2 in Ataxia and cerebellar anomalies - narrow panel Level 2: Neurology Version 8.63 Latest signed off version: v8.0 (30 Apr 2025) Component of the following Super Panels: Hereditary ataxia and cerebellar anomalies - childhood onset	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Expert list Phenotypes Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688 Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy, OMIM:619090
Green MORC2 in Severe microcephaly Level 2: Neurology Version 8.31 Latest signed off version: v8.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Literature Phenotypes Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688 Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy, OMIM:619090
Green MORC2 in DDG2P Version 6.424 Latest signed off version: v6.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green DD-Gene2Phenotype Phenotypes MORC2 - axonal neuropathy
Green MORC2 in Hereditary neuropathy Level 3: Motor and Sensory Disorders of the PNS Level 2: Neurology and neurodevelopmental disorders Version 1.506	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources South West GLH NHS GMS London North GLH Expert Review Green Literature Phenotypes Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688 Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy, OMIM:619090
Amber MORC2 in Monogenic hearing loss Level 2: Audiology Version 5.57 Latest signed off version: v5.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber Literature Phenotypes Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688 Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy, OMIM:619090
Green MORC2 in Intellectual disability Level 2: Developmental disorders Version 9.279 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Literature Phenotypes Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688 Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy, OMIM:619090
Amber MORC2 in Hereditary ataxia with onset in adulthood Level 2: Neurology Version 8.23 Latest signed off version: v8.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber London North GLH NHS GMS Wessex and West Midlands GLH Phenotypes Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688
Amber MORC2 in Retinal disorders Level 2: Ophthalmology Version 8.86 Latest signed off version: v8.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber Literature Phenotypes Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy, OMIM:619090 Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688 Retinal dystrophy, HP:0000556 Tags Q1_26_promote_green Q1_26_NHS_review
Green MORC2 in Hereditary neuropathy or pain disorder Level 2: Neurology Version 7.36 Latest signed off version: v7.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources South West GLH Literature Expert Review Green London North GLH NHS GMS South West GLH NHS GMS London North GLH Phenotypes Charcot-Marie-Tooth disease, axonal, type 2Z, OMIM:616688 Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy, OMIM:619090