T

T brachyury transcription factor
OMIM: 601397, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels

Red T in Currarino triad


Version 1.1

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Sacral agenesis with vertebral anomalies,615709
Tags
  • new-gene-name

Red T in Familial Neural Tube Defects


Version 1.10

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Other
Phenotypes
  • Susceptibility to neural tube defects
Tags
  • new-gene-name

Red T in Tumour predisposition - childhood onset

Level 3: Childhood Tumours
Level 2: Tumour syndromes
Version 2.16
Signed off v.2.5 on 4 Mar 2020

review Not set
Sources
  • Expert Review Red
  • Expert List
Tags
  • new-gene-name

Green T in Sarcoma cancer susceptibility

Level 3: Pertinent cancer susceptibility gene panel
Level 2: Cancer Programme
Version 1.15

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Familial Chordoma
  • Chordoma
Tags
  • new-gene-name
  • cnvs

Red T in Non-syndromic familial congenital anorectal malformations

Level 3: Gastrointestinal disorders
Level 2: Gastroenterological disorders
Version 1.6

review Not set
Sources
  • Literature
Phenotypes
  • sacral agenesis
  • anorectal atresia
Tags
  • new-gene-name

Green T in Sarcoma susceptibility


Version 1.5
Signed off v.1.2 on 18 Feb 2020

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • NHS GMS
  • Expert Review Green
  • Expert list
Phenotypes
  • Familial Chordoma
  • Chordoma