Sarcoma susceptibility

Gene: T

Green List (high evidence)

T (T brachyury transcription factor)
EnsemblGeneIds (GRCh38): ENSG00000164458
EnsemblGeneIds (GRCh37): ENSG00000164458
OMIM: 601397, Gene2Phenotype
T is in 6 panels

3 reviews

Rebecca Foulger (Genomics England curator)

Green List (high evidence)

As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: agreed that there is enough evidence to rate this gene green.
Created: 23 Jul 2019, 3:16 p.m. | Last Modified: 23 Jul 2019, 3:16 p.m.
Panel Version: 0.2

Louise Daugherty (Genomics England Curator)

Added new-gene-name tag, new approved HGNC gene symbol is TBXT
Created: 25 May 2018, 8:47 a.m.

Ellen McDonagh (Genomics England Curator)

This gene was reviewed by Lara Hawkes (Cancer Clinical Team, Genomics England) and agrees this should be included on this panel.
Created: 20 Aug 2018, 1:30 p.m.
Gene and evidence provided by Adrienne Flanagan, UCL.
Created: 14 May 2018, 4:01 p.m.

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • NHS GMS
  • Expert Review Green
  • Expert list
Phenotypes
  • Familial Chordoma
  • Chordoma
OMIM
601397
Clinvar variants
Variants in T
Penetrance
None
Publications
Panels with this gene

History Filter Activity

23 Jul 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Rebecca Foulger (Genomics England curator)

gene: T was added gene: T was added to Sarcoma susceptibility. Sources: NHS GMS,Expert Review Green Mode of inheritance for gene: T was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: T were set to 23064415; 19801981 Phenotypes for gene: T were set to Familial Chordoma; Chordoma