Sarcoma susceptibility
Gene: TAdded new-gene-name tag, new approved HGNC gene symbol is TBXTCreated: 10 May 2022, 3:20 p.m. | Last Modified: 10 May 2022, 3:20 p.m.
Panel Version: 1.69
Comment on phenotypes: This gene is also associated with {Neural tube defects, susceptibility to}, OMIM:182940; Sacral agenesis with vertebral anomalies, OMIM:615709Created: 11 Mar 2021, 10:24 a.m. | Last Modified: 11 Mar 2021, 10:24 a.m.
Panel Version: 1.18
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: agreed that there is enough evidence to rate this gene green.Created: 23 Jul 2019, 3:16 p.m. | Last Modified: 23 Jul 2019, 3:16 p.m.
Panel Version: 0.2
Added new-gene-name tag, new approved HGNC gene symbol is TBXTCreated: 25 May 2018, 8:47 a.m.
This gene was reviewed by Lara Hawkes (Cancer Clinical Team, Genomics England) and agrees this should be included on this panel.Created: 20 Aug 2018, 1:30 p.m.
Gene and evidence provided by Adrienne Flanagan, UCL.Created: 14 May 2018, 4:01 p.m.
Publications for gene: T were set to 23064415; 19801981; 34837714
Publications for gene: T were set to 23064415; 19801981
Tag new-gene-name tag was added to gene: T.
Phenotypes for gene: T were changed from Susceptibility to Chordoma; Chordoma (disease), MONDO:0008978 to Chordoma (disease), MONDO:0008978
Phenotypes for gene: T were changed from Familial Chordoma; Chordoma to Susceptibility to Chordoma; Chordoma (disease), MONDO:0008978
gene: T was added gene: T was added to Sarcoma susceptibility. Sources: NHS GMS,Expert Review Green Mode of inheritance for gene: T was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: T were set to 23064415; 19801981 Phenotypes for gene: T were set to Familial Chordoma; Chordoma