Sarcoma susceptibilityGene: TNFRSF11A
Gene and evidence provided by Adrienne Flanagan, UCL. Comment from Adrienne on the evidence for this gene: "TNFRSF11A is linked to familial Pagetic bone disease and Pagetic bone disease is associated with sarcoma…although the body of evidence linking TNFRSF11A and osteosarcoma is limited."
Created: 14 May 2018, 3:49 p.m.
Source NHS GMS was added to TNFRSF11A.
gene: TNFRSF11A was added gene: TNFRSF11A was added to Sarcoma susceptibility. Sources: Expert Review Red Mode of inheritance for gene: TNFRSF11A was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: TNFRSF11A were set to 15758393; 12673693; 11351498 Phenotypes for gene: TNFRSF11A were set to Paget disease of bone; Polyostotic osteolytic dysplasia (hereditary expansile); Osteosarcoma