Sarcoma cancer susceptibility

Gene: T

Green List (high evidence)

T (T brachyury transcription factor)
EnsemblGeneIds (GRCh38): ENSG00000164458
EnsemblGeneIds (GRCh37): ENSG00000164458
OMIM: 601397, Gene2Phenotype
T is in 6 panels

2 reviews

Louise Daugherty (Genomics England Curator)

Added new-gene-name tag, new approved HGNC gene symbol is TBXT
Created: 25 May 2018, 8:47 a.m.

Ellen McDonagh (Genomics England Curator)

This gene was reviewed by Lara Hawkes (Cancer Clinical Team, Genomics England) and agrees this should be included on this panel.
Created: 20 Aug 2018, 1:30 p.m.
Gene and evidence provided by Adrienne Flanagan, UCL.
Created: 14 May 2018, 4:01 p.m.

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
Phenotypes
  • Familial Chordoma
  • Chordoma
Tags
new-gene-name cnvs
OMIM
601397
Clinvar variants
Variants in T
Penetrance
None
Publications
Panels with this gene

History Filter Activity

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Ellen McDonagh: Gene and evidence provided by

14 May 2018, Gel status: 3

Set mode of inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for T was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

14 May 2018, Gel status: 3

Set publications

Ellen McDonagh (Genomics England Curator)

Publications for T were set to 19801981; 23064415

14 May 2018, Gel status: 3

Set publications

Ellen McDonagh (Genomics England Curator)

Publications for T were set to 19801981

14 May 2018, Gel status: 3

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

14 May 2018, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

T was added to Sarcoma pertinent cancer susceptibility panel. Sources: Expert list

14 May 2018, Gel status: 1

Created

Ellen McDonagh (Genomics England Curator)

T was created by Ellen McDonagh